描述
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation.FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. vascular repair, traumatic brain injury (TBI). FGF-basic is a critical component of human embryonic stem cell culture medium. In addition, FGF-basic protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, FGF-basic is regarded as a target for cancers chemopreventive and therapeutic strategies.
